Kanye West — Fires Back at Ray J … You’re Lame and You Know It!

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Kanye West decided it”s finally time to destroy Ray J — and last night he blasted his wife”s sex tape partner on national TV … going straight after Ray”s manhood.

West made a surprise appearance on “Late Night with Jimmy Fallon” to perform his hit “Bound 2” — but during the song, he changed some of the lyrics to attack Ray:

“Brandy’s little sister lame man he know it now … When a real brother hold you down, you ‘sposed to drown.”

We”re guessing Kanye is finally responding to Ray”s song, “I Hit It First” … in which Ray bragged about bangin” Kim Kardashian before Kanye did.

But the best part of Kanye”s attack … the legendary Charlie Wilson punctuating the venomous lyrics with a “shabadabaweeeeeee”

It”s awesome.